A PRIMER ON METAGENOMICS.

A primer on metagenomics.

Metagenomics is a discipline that enables the genomic study of uncultured microorganisms.Faster, cheaper sequencing technologies and the ability to sequence uncultured microbes sampled directly from their habitats are expanding and transforming our view of the microbial world.Distilling meaningful information from the millions of new genomic sequen

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AHP6 inhibits cytokinin signaling to regulate the orientation of pericycle cell division during lateral root initiation.

In Arabidopsis thaliana, lateral roots (LRs) initiate from anticlinal cell divisions of pericycle founder cells.The Washing Machine Timer formation of LR primordia is regulated antagonistically by the phytohormones cytokinin and auxin.It has previously been shown that cytokinin has an inhibitory effect on the patterning events occurring during LR f

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Distinct target genes and effector processes appear to be critical for p53-activated responses to acute DNA damage versus p53-mediated tumour suppression

The p53 tumour suppressor is the most frequently mutated gene in human cancer.This transcription factor can be activated by diverse cellular stresses, including DNA damage and oncogene activation.Through transcriptional induction of appropriate target genes, p53 can stimulate activity in a broad range of effector pathways, most notably cell cycle a

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